Book cover of Suggestible You by Erik Vance

Erik Vance

Suggestible You

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Your brain doesn’t just perceive the world; it creates it based on expectations. What can this power of suggestion teach us about ourselves?

1. Placebos Trigger the Brain's Expected Outcomes

The placebo effect showcases the brain’s incredible power to transform expectations into reality. When you take a sugar pill believing it to be medicine, your brain often creates the expected healing effect. Even though the pill lacks active ingredients, the body responds as if the treatment were real.

One striking example involves homeopathy. Though homeopathic remedies contain substances so diluted they are often just water, many patients report genuine improvements in their health. This stems from a patient's expectations and the stories they associate with the treatment. These narratives give the brain a framework to respond to the placebo.

A moving account involved a woman trapped in depression linked to a childhood trauma. A homeopath prescribed melted snow in a vial, representing the freezing night her family fled during World War II. Though it was just water, the suggestion tied to her personal narrative allowed her to recover and reconnect with others. This underscores just how strongly beliefs can shape outcomes.

Examples

  • Taking painkillers but feeling better before they take physical effect shows placebo influence.
  • Homeopathic remedies gain loyalty despite lacking active ingredients; the belief in them heals.
  • Trauma and healing stories, like the woman prescribed melted snow, highlight placebo power.

2. Your Body Produces Natural Painkillers

The body is a self-repairing machine, equipped with chemicals that can dull pain and elevate mood. These substances, such as endorphins and dopamine, are activated by the brain, often influenced by suggestions like those from a placebo.

Endorphins, the body’s natural opioids, are released when we feel pain, helping to mitigate its impact. Placebos trigger these same reactions by activating areas in the brain associated with natural opioid production. Endocannabinoids (similar to compounds in cannabis) and serotonin also play roles in reducing pain and promoting relaxation.

For conditions like chronic pain, which affects millions, placebos stimulate the body to release its chemical soldiers. Studies show that patients receiving mock treatments often feel genuine relief because their belief in the treatment kickstarts these processes naturally.

Examples

  • Placebo trials for chronic pain trigger endorphin release, mimicking actual treatments.
  • Dopamine, the reward hormone, increases when participants believe they’re improving.
  • Endocannabinoids also respond to placebo processes, aiding pain and nausea relief.

3. Placebo Success May Depend on Your Genes

Not everyone experiences the full effects of placebos, and scientists are investigating why. Early studies suggest that genetic variations could explain why some people are exceptionally responsive.

In one trial for Parkinson’s disease, a patient displayed extraordinary recovery despite receiving a placebo. His handwriting improved, and he regained motor control. It turns out that some genetic markers, particularly those related to dopamine regulation, align with higher placebo responsiveness.

Future research could use genetic insights to predict responsiveness, improving personalized treatment plans. Those with high placebo responsiveness might thrive with alternative therapies, while others could rely more on conventional methods.

Examples

  • A Parkinson’s study highlighted dramatic placebo recovery tied to dopamine regulation.
  • Genetic markers were found to correlate with placebo responses in pain and mood disorders.
  • Predicting placebo responsiveness could help tailor treatments to individuals.

4. Nocebo Effects Can Cause Real Harm

The same suggestibility that helps placebos heal can create harm through the nocebo effect. When people expect pain or illness, their body often complies.

Historical examples include a woman who suffered an allergic reaction and asthma attack upon seeing a rose. The twist? The rose was fake. Her symptoms stemmed entirely from her belief in its harmful effect. Similarly, media stories about health scares often cause waves of nocebo symptoms unrelated to actual exposure.

Nocebos demonstrate that fear can influence our health as much as hope can—making us sick based solely on expectation. Recognizing these effects provides opportunities to minimize harm, such as reducing panic during health scares or being cautious about how information is shared.

Examples

  • A woman had a severe asthma attack due to a fake rose she believed was real.
  • Media panic over nonexistent risks, like wind turbine syndrome, triggers real symptoms.
  • The 2014 Ebola scare caused mass hysteria despite very few actual cases in the US.

5. Hypnosis Puts Suggestibility Front and Center

Hypnosis might seem like a stage trick, but it demonstrates our brain’s impressive responsiveness to suggestion. Under hypnosis, people enter a focused state that allows them to access altered perceptions and even reduce pain.

Burn survivors have benefitted from hypnotic suggestions to withstand dressing changes. When hypnotists craft specific imagery tailored to individuals’ experiences, patients relieve pain and achieve control over their responses. While only about 10% of people are highly susceptible, hypnotists have helped patients in surgeries using nothing but focused suggestion.

Hypnosis blends art and science, and its success depends on the skill of the practitioner and the person’s natural suggestibility. Brain studies suggest people with slower brain wave activity find hypnosis more effective.

Examples

  • Burn victims in pain have undergone non-surgical procedures by hypnotic pain relief.
  • A patient had an ax removed from his neck under hypnosis, avoiding traditional anesthesia.
  • Brain activity studies show slower electrical waves correlate to deeper hypnotic states.

6. False Memories Show How Fallible Memory Is

Memory isn’t as reliable as we’d like to think—it’s easily influenced. False memories demonstrate that our recollections are shaped and reshaped every time we access them, meaning they can be altered by suggestion.

This phenomenon is clear in studies, like one after the 1986 Challenger explosion, where students’ recall of where they were drastically changed over three years. Though their memories felt more vivid, they were less accurate. Each retrieval reconstruction added fictional elements, reshaping the narrative.

False memories reveal how suggestible we are, not only about the past but also in our current relationships or disputes. Being aware of these tendencies allows us to question our memories and remain open to new perspectives.

Examples

  • Challenger explosion recall differed greatly between initial accounts and retold memories.
  • Suggestible memory techniques have helped eyewitnesses describe imagined crimes.
  • Memories of childhood events often blur accuracy due to repeated conversations.

7. Your Choices Are Shaped by Expectations

Everyday decisions, like choosing wine or buying snacks, are influenced by appearance and preconceived notions. Packaging, price, and branding shape our expectations, which, in turn, can change our perceptions.

A milkshake experiment illustrated this. When participants thought they were drinking a low-calorie shake, their bodies produced more hunger hormones afterward—even though it had the same calories as a "decadent" shake. The label changed how their brain and stomach processed the drink.

This shows that our brains trick us into better or worse decisions based on subtle suggestions. Awareness of this can help us recognize when attraction to a product is based on reality—or clever marketing.

Examples

  • Milkshake labels fooled participants into different ghrelin hormone responses.
  • Expensive packaging enhances wine’s perceived flavor even if the wine is identical.
  • Advertisement slogans and imagery prime our excitement for products.

8. Addiction Taps into the Brain's Suggestive Loop

Addiction reveals just how powerfully expectation shapes behavior and physiology. In the addicted brain, dopamine release from substances like alcohol creates a cycle of diminishing pleasure and increased cravings.

As expectations for relief or high grow, the brain adapts by reducing natural dopamine production. This leaves addicts relying on substances for even basic enjoyment. Therapies that reshape these expectations, from mindfulness to placebo-linked strategies, are becoming viable tools in recovery.

This demonstrates how understanding the power of suggestibility could help unlock breakthrough treatments for some of society's hardest challenges, like addiction.

Examples

  • Dopamine plummets after long-term drug use, increasing dependence due to brain rewiring.
  • Stories of placebo-assisted addiction recovery show rewiring expectation loops works.
  • Mind-body approaches integrate suggestion to replace cravings with new rewards.

9. Use Suggestion to Your Advantage

Finally, you can harness this incredible mind-body connection in your own life. By understanding your personal suggestibility and preferences, you can make choices that improve mood, health, and resilience.

Start by paying attention to your responses. Do certain routines always leave you invigorated? Does your body react to placebo-like treatments? These insights can help you design a life that works harmoniously with your expectations.

However, this power requires balance. Stick to safe choices, avoid wild claims, and anchor yourself in practical, informed decision-making.

Examples

  • Crafting motivational storytelling can enhance placebo-like results in well-being.
  • Positive practices like meditation and affirmations harness expectation’s healing power.
  • Avoiding financial risks or unsafe promises ensures sound applications of suggestion.

Takeaways

  1. Study your habits and emotional responses to find what narratives and routines inspire you most—align your goals around what "fits" naturally.
  2. Experiment with safe ways to tap into the power of suggestibility, such as mindfulness, affirmations, or small lifestyle tweaks.
  3. Recognize the limits of suggestion as a tool and combine it with proven medical or scientific approaches when addressing serious issues.

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